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SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz

  • Based on 826 reviews
Condition: New
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$295.00 Why this price?

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To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

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Availability: In Stock.
Fulfilled by Amazon

Arrives Tuesday, Apr 8
Order within 54 minutes
Available payment plans shown during checkout

Color: clear


Skin Type: All, Combination, Sensitive


Product Benefits: TNS Advanced+ Serum is proven to smooth the appearance of wrinkles & fine lines, target sagging, & rejuvenate skin. See more


Use for: Face


Scent: Aloe


Special Ingredients: Next-generation growth factor blend — supports healthy skin functions


Product Dimensions ‏ : ‎ 2 x 2 x 7 inches; 4 ounces


Item model number ‏ : ‎ 96395


UPC ‏ :


Country of Origin ‏ : ‎ USA


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Apr 8

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Expensive but works
This product works but it is very expensive and I found that for the price and the amount of product you get is not worth me purchasing it again. I suppose if I only used it once a week it would have lasted me longer. Or if it was in a jar and not a pump. But I used it daily and it was gone in month. One time purchase for me unfortunately. ... show more
Reviewed in the United States on June 22, 2024 by shopoholic

  • ADDICTED to Skin Medica
I have been using Skin Medica products for 17+ years. The TNS is an Incredible skin cream. When you first start using it, you’ll notice a little redness on your forehead - forget it. It’ll go away. I stopped using it after six months in the beginning just to see if there was a difference in my skin. There was a total difference! I needed more moisturizer. My skin felt dry, the texture looked different and my skin looked dull.. I see that people have problems with the pump. Just shake it or turn it upside down for a little bit and it’ll start coming back out again. As for the price, it takes a year to get rid of this product, using it twice a day religiously. It only takes one pump to cover your whole face and I also do my neck. I usually go brush my teeth to give it a chance to soak in before I put on my moisturizer. I just turned 73 and there is no one who thinks I am even close to my age….I am addicted! This pic is out of the shower, no makeup, no touch up. ... show more
Reviewed in the United States on March 16, 2025 by Podi P Podi P

  • BE AWARE OF SUBSCRIBE AND SAVE HENCE 1 STAR - PRODUCT IS A 5 STAR
Be aware of subsribe and save for this product. I have subscribe and save for this since it cost alot and it was cheaper that way. I did not need my back up one until today. When I opened it, it would not expel the cream in the right pump. Only the left side of the pump worked. I tried to exchange it, but the last date to return it was in October. I called customer service since Amazon has always been so wonderful to help with problems. However, this time they would not help. It is past the return window, even though it is broken! So my advice to you is it is a wonderful product although it is pricey, I will not buy another for awhile (because of the cost). If you have subscribe and save for this product, my whole reason for this review is to tell you when you receive your bottle check it right away! I wish I had. The only problem with that is now it won't be fresh if you don't need it for awhile. Since this has happened to my pump, I have checked into this product and it looks as though this has been a problem for some with only one side of the pump working. All the more reason to check it works when you receive it. ... show more
Reviewed in the United States on November 26, 2024 by Debbie J Habegger

  • Best product on the market IMO
I noticed results right away… with a week. I started using for fine lines around my eyes … after having a baby my skin changed so much! I’m still breastfeeding so can’t do Botox or filler by now I don’t need to! I did blow through this bottle in a month though… it’s pricey but it did work rather well for me. I use this along with tns recovery and the hydrated. It’s been a gamechanger. ... show more
Reviewed in the United States on March 22, 2025 by Ashley A.

  • If you’re on the fence, buy it.
Given the price, there is a part of me that didn’t want this to work so I wouldn’t have to add it to my budget. I am 6 days in and writing this review because I am already seeing significant results. I have a strong routine (vitamin c, hyaluronic, niacinamide, SPF, others) but continue to struggle with retinol sensitivity. Even after years of use, I can still only tolerate retinol 1-2x per week and have been looking for another anti aging serum to supplement the other 5-6x nights. This is it. It goes on light, absorbs easily, and I have had zero sensitivity even with nightly use. My skin is positively glowing! I’m hoping I don’t have the pump issue others have described, but will buy more even if I do. Looking forward to results in 30 days and beyond. ... show more
Reviewed in the United States on October 12, 2024 by jmstiles

  • Excellent Facial Lotion
Love this product - been using for years. Does wonders to keep skin looking good and healthy. Not a 5 star rating because the product is designed to mix two lotions together as you use it. More than once I have had issues with one side not working. If you purchase ahead, which I have done when on sale, and the return/contact seller window closes, you are out of luck on Amazon. TNS hard to reach and does not respond. ... show more
Reviewed in the United States on January 22, 2025 by DB

  • The bottle is flawed.
The product is incredible, the serum and lotion work, however, SkinMedica need to work on their chambers! I lose quite a bit of product when I’m troubleshooting. Sometimes the lotion pumps out of both chambers, and sometimes the serum pumps out of both chambers. I have to really work on getting them to work together & lose product whilst doing so. I’d love to give it 5 stars but the bottle is terrible. I gave it 3 stars because the serum & lotion work. ... show more
Reviewed in the United States on May 8, 2024 by Christine

  • Stupid expensive but works
I can’t say I look any younger but my skin does indeed have a nicer feel. Not a fan of the pump design. Feels like you can’t get everything out which for this price, you’ll want to.
Reviewed in the United States on September 16, 2024 by runcix

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