Search  for anything...

Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 6-Month Supply

  • Based on 73,131 reviews
Condition: New
Checking for product changes

Buy Now, Pay Later


As low as $11.50 / mo
  • – 6-month term
  • – No impact on credit
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout. Payment plans are offered through our trusted finance partners Klarna, PayTomorrow, Affirm, Afterpay, Apple Pay, and PayPal. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Selected Option

Free shipping on this product
This item's return window has been extended for the holiday season: Returnable until Jan 31, 2025

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

To initiate a return, please visit our Returns Center.

View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Thursday, Dec 26
Order within 23 hours and 2 minutes
Available payment plans shown during checkout

Size: 6-Pack


Style: Large Cat only


Features

  • Advantage II Large Cat is a leading brand in cat flea treatment and prevention for large cats over 9 lbs., at least 8 weeks of age
  • Vet-recommended, easy-to-apply monthly topical treatment no hard-to-swallow pills, no prescription needed
  • Delivers total flea protection kills adult fleas, flea larvae and flea eggs through contact
  • Same-day effectiveness kills fleas within 12 hours of application and keeps working for 30 days
  • Fragrance-free formula, waterproof after 24 hours of application

Description

Advantage II Large Cat is a vet-recommended, leading brand in cat flea protection. Advantage II Large Cat flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your cat or kitten. Within 12 hours of application, Advantage II Large Cat topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your cat to die. This treatment works hard for 30 days following application, effectively breaking the flea life cycle, controlling existing flea infestations and preventing further infestations all month long.Fleas not only cause discomfort; they can also pose other health risks. Monthly use of Advantage II Large Cat is important to protect your cat against fleas that may cause transmission of tapeworms, Flea Allergy Dermatitis and flea bite anemia.That’s why Advantage II Large Cat makes applying treatment simple. This convenient, spot-on application goes on the back of your cat’s neck at the base of the skull. You’ll simply place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. It goes on in seconds! It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that Advantage II Large Cat is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects.Advantage II Large Cat flea protection is effective on both indoor and outdoor cats. Your cat should be at least 8 weeks old and weigh over 9 lbs. to use Advantage II Large Cat.For the ultimate convenience in care, Advantage II Large Cat is available over the counter – no prescription needed. And, you can stock up with a subscription for regular doorstep deliveries so you never miss a monthly treatment. Advantage II Large Cat is a trademark of Elanco or its affiliates.

Brand: Advantage


Item Form: Topical


Scent: Unscented


Item Weight: 0.8 Ounces


Active Ingredients: Imidacloprid 9.10%, Pyriproxyfen 0.46%


Item Volume: 4.8 Milliliters


Target Species: Cat


Allergen Information: Allergen-Free


Age Range (Description): 8 weeks and older


UPC:


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1.38 x 4.38 x 6.63 inches; 0.8 ounces


Manufacturer recommended age ‏ : ‎ 1 month and up


Item model number ‏ : ‎ 86336774


Date First Available ‏ : ‎ March 2, 2011


Manufacturer ‏ : ‎ Elanco US Inc


Country of Origin ‏ : ‎ Germany


Best Sellers Rank: #178 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Cat Flea Drops


#1 in Cat Flea Drops:


Item Weight: 0.8 ounces


Manufacturer: Elanco US Inc


Country of Origin: Germany


Item model number: 86336774


Date First Available: March 2, 2011


Item Package Dimensions L x W x H: 6.81 x 4.29 x 1.34 inches


Item Dimensions LxWxH: 1.38 x 4.38 x 6.63 inches


Item Weight: 0.8 Ounces


Brand Name: Advantage


Target Audience Keyword: house-cats


Directions: Application Instructions 1. Use only on cats. 2. Hold applicator tube in an upright position. Pull cap off tube. 3. Turn the cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. 4. Part the hair at the base of the cat’s skull until skin is visible. 5. Evenly apply the entire contents of the Advantage II tube directly on the skin by squeezing the entirety of the contents in that one spot. Do not get this product in your cat’s eyes, or allow your cat to ingest this product.


Model Name: Advantage II


Color: Large Cat only


Size: 6-Pack


Age Range Description: 8 weeks and older


Care Instructions: Topical


Number of Items: 1


Style: Large Cat only


Breed Recommendation: Large


Specific Uses for Product: Parasites


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Thursday, Dec 26

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Very effective
Size: 2-Pack Style: Large Cat only
My cat had been on a less expensive, once a month flea treatment for several years. However it seemed to lose its effectiveness. He lives inside 70 % of the time, but he started having a flea issue, So I tried this instead and he is very happy. He has not had any issues with fleas since I started this 5 months ago. It is easy to apply. Plus he is 14 pounds. So he’s a big boy and a lot of flea medicine is meant for a cat under 10 pounds. ... show more
Reviewed in the United States on December 1, 2024 by Amazon Customer Amazon Customer

  • Absolutely worth the price
Size: 4-Pack Style: Large Cat only
I’ve used this product multiple times for my cats, and it works perfectly every single time. It’s highly effective, easy to use, and has never caused any issues for my pets. I’ve been consistently impressed with the results, and it has become my go-to solution for keeping my cats flea-free. I’m incredibly satisfied and would recommend it to anyone looking for a reliable flea treatment. ... show more
Reviewed in the United States on December 1, 2024 by Roman

  • Kills fleas and flea eggs
Size: 2-Pack Style: Large Cat only
I've tried other flea medicine that hasn't worked and have had to wait weeks before using a better treatment. This is the heavy duty stuff that will annihilate a flea infestation. My cats hate the smell of it, but they don't seem to get any skin irritation. Great product, worth the money.
Reviewed in the United States on November 30, 2024 by Jeanette V.

  • It works
Size: 2-Pack Style: Large Cat only
Out of all the different brands I've tried for over the counter, this is the only one that seems to work. If you have a mild infestation or bad, be sure to give your cat a flea shampoo bath first. Then let them dry off and apply this. This is best used as prevention and for small infestation. It works really well. After getting rid of fleas it prevents infestation for around a month. Just make sure you stay on top of getting this monthly. ... show more
Reviewed in the United States on November 29, 2024 by Castiel

  • Advantage works
Size: 6-Pack Style: Large Cat only
Well, bottom line is that these drops work. I applied these drops less than a week ago to 2 cats and they're not scratching nearly as much. Ok, so my mom adopted 2 cats last year. They were fine all year until they started going out back. Then the scratching started. I have to preface by saying one of the cats is still mostly wild and is just getting use to a fews strokes on her back before she runs away. That said, I knew I had to be quick. With a treat in 1 hand and an open Advantage tube in the other I was able to distract her with food and just pressed the tube into the nape of her neck & squeezed. Shockingly, it worked. I had fears that it would be all over her fur, but pressing it down ensured contact with the skin. Unlike other brands I've tried in the past, Advantage is just a small amount of liquid. Honestly, all flea meds scare me as I know they must be really strong to do the job they do. After I applied it, both cats tolerated it, but then they reacted. The wild one kept running all over the house and the tame one was restless for a few hours. It bothers me to see them like that BUT I also know that fleas can kill a cat. Seriously, I've seen it happen. Fleas make cats sick and cause them to be anemic. So, do I give my cats meds that will cause a bad reaction for a few hours, then protect them for the next 30 days or do I do nothing and let them scratch nonstop knowing that the fleas are harming them with every bite? It was an easy decision. It's been almost a week and I can see they're so much more comfortable from not having to scratch all the time. Sure they still scratch a little - but that's normal - the bites are still healing and any new flea that bites them will die. I read that you have to use flea drops for like 5 months straight to ensure you eliminate all the fleas that may be hiding out in the surrounding areas. I'm willing to do it. You can tell when your cats are happy, and I know these 2 are far more comfortable than they were a week ago. ... show more
Reviewed in the United States on June 15, 2024 by A. Mitchell

  • Worked when other product failed.
Size: 2-Pack Style: Large Cat only
Last year, My indoor cats somehow all popped up with fleas. We know it can happen so we have always treated with Frontline during the summer months...however despite being indoors and being treated they still got fleas. Everyone was scratching ,licking themselves, followed by puking all the hair they licked off all over the house. Decided to try something different which lead me to this product.. within 2 weeks the itching had stopped and the fleas were gone... here we are a year later and using again for the summer and no fleas. This stuff works. I have 3 cats of all different weights so I must purchase for both small and large cats.. this treatment is not one size fits all. It goes by weight. The small version goes on rather quickly over a small area while the larger version has alot in it and requires alot of more are to place it on. Overall it works and is affordable for an owner of 3 cats. ... show more
Reviewed in the United States on June 5, 2024 by DK

  • Only thing that worked!
Size: 4-Pack Style: Large Cat only
I tried flea collars and oral pills and nothing worked but this… TWO PERSON JOB. I’ve bought it 3 times now. The first attempt I put it too low on my cats neck and he licked it and FREAKED out I felt so so awful he was running around and drooling. He ended up being totally fine but he is scared of this medicine now. I tried to put it on by myself and the cats wriggled around so this happened. I was too scared to try it again for a while but the fleas were getting out of control. The second time my finance held the cats while I put it very high up on their necks and everything worked perfect! ... show more
Reviewed in the United States on December 2, 2024 by Love

  • Works But Not For Long
Size: 6-Pack Style: Large Cat only
The first time I used this product on my two large cats, it was apparent that it worked quickly. One of our cats had chewed off his fur on his belly and legs before treatment and his hair began to grow back within a few days of treatment. Unfortunately, both cats began scratching again after 10 days. Since this product allows reapplication every week for up to 4 times, I simply reapplied and the product lasted 15 days before the treatment stopped working. I have now treated them for a third time and will wait to see how long the treatment is effective. I also vacuum almost daily, spray with Vet's Best Home Spray, and check the cats daily with a flea comb. I found live fleas on both cats at the end of the 10 day and the 15 day treatments. Mine are inside only cats and the only pets. Since I used the Elanco Advantage II, I have ordered the Bayer Advantage II to see if that makes a difference in the length of effectiveness. I found application to be very easy and my cats have had no adverse reaction to the medication. I just wish it worked longer than it does. Treatments were done exactly as directed. ... show more
Reviewed in the United States on August 4, 2024 by DONNA J. TODD

Can't find a product?

Find it on Amazon first, then paste the link below.