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Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 2-Month Supply

  • Based on 74,282 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon

Arrives Tuesday, Apr 29
Order within 8 hours and 21 minutes
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Size: 2-Pack


Style: Large Cat only


Features

  • Advantage II Large Cat is a leading brand in cat flea treatment and prevention for large cats over 9 lbs., at least 8 weeks of age
  • Vet-recommended, easy-to-apply monthly topical treatment no hard-to-swallow pills, no prescription needed
  • Delivers total flea protection kills adult fleas, flea larvae and flea eggs through contact
  • Same-day effectiveness kills fleas within 12 hours of application and keeps working for 30 days
  • Fragrance-free formula, waterproof after 24 hours of application

Description

Advantage II Large Cat is a vet-recommended, leading brand in cat flea protection. Advantage II Large Cat flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your cat or kitten. Within 12 hours of application, Advantage II Large Cat topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your cat to die. This treatment works hard for 30 days following application, effectively breaking the flea life cycle, controlling existing flea infestations and preventing further infestations all month long.Fleas not only cause discomfort; they can also pose other health risks. Monthly use of Advantage II Large Cat is important to protect your cat against fleas that may cause transmission of tapeworms, Flea Allergy Dermatitis and flea bite anemia.That’s why Advantage II Large Cat makes applying treatment simple. This convenient, spot-on application goes on the back of your cat’s neck at the base of the skull. You’ll simply place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. It goes on in seconds! It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that Advantage II Large Cat is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects.Advantage II Large Cat flea protection is effective on both indoor and outdoor cats. Your cat should be at least 8 weeks old and weigh over 9 lbs. to use Advantage II Large Cat.For the ultimate convenience in care, Advantage II Large Cat is available over the counter – no prescription needed. And, you can stock up with a subscription for regular doorstep deliveries so you never miss a monthly treatment. Advantage II Large Cat is a trademark of Elanco or its affiliates.

Brand: Advantage


Item Form: Topical


Scent: Unscented


Item Weight: 0.04 Pounds


Active Ingredients: Imidacloprid, Pyriproxyfen


Item Volume: 1.6 Milliliters


Allergen Information: Allergen-Free


Dog Breed Size: Large


Age Range (Description): 8 weeks and older


UPC:


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1 x 4.38 x 4.75 inches; 0.64 ounces


Item model number ‏ : ‎ 86336677


Date First Available ‏ : ‎ September 1, 2014


Manufacturer ‏ : ‎ Elanco US Inc


Country of Origin ‏ : ‎ Germany


Best Sellers Rank: #65 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Cat Flea Drops


#1 in Cat Flea Drops:


Customer Reviews: 4.5 4.5 out of 5 stars 74,282 ratings


Item Weight: 0.64 ounces


Manufacturer: Elanco US Inc


Country of Origin: Germany


Item model number: 86336677


Date First Available: September 1, 2014


Item Package Dimensions L x W x H: 4.8 x 4.33 x 0.87 inches


Item Dimensions LxWxH: 1 x 4.38 x 4.75 inches


Item Weight: 0.04 Pounds


Brand Name: Advantage


Target Audience Keyword: house-cats


Directions: Application Instructions 1. Use only on cats. 2. Hold applicator tube in an upright position. Pull cap off tube. 3. Turn the cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. 4. Part the hair at the base of the cat’s skull until skin is visible. 5. Evenly apply the entire contents of the Advantage II tube directly on the skin by squeezing the entirety of the contents in that one spot. Do not get this product in your cat’s eyes, or allow your cat to ingest this product.


Model Name: Advantage II


Color: Large Cat only


Size: 2-Pack


Age Range Description: 8 weeks and older


Number of Items: 1


Style: Large Cat only


Breed Recommendation: Large


Specific Uses for Product: Parasites


Frequently asked questions

No, the Advantage II is specifically designed for large cats over 9 pounds. For smaller cats or kittens, it's suggested to use a different variation of Advantage.

This package provides a 2-month supply. It's recommended to apply the treatment monthly for continuous flea protection.

Yes, Advantage II for Large Cats is a vet-recommended flea treatment and prevention product.

Advantage II works by killing fleas through contact, meaning they don’t have to bite your cat to die. It kills fleas within 12 hours of the first application and prevents further flea infestations for up to a month.

Top Amazon Reviews

🚀 Abunda's Overview

This is our summary and key points to consider based on customer reviews.


Advantage II Large Cat is a well-reviewed flea treatment for cats over nine pounds. It efficiently kills adult fleas, their larvae, and eggs, causing a significant reduction in flea infestations within days. The formula, which is applied topically, begins working in twelve hours and is effective for thirty days. It is praised for its ease of use, as no prescription is needed, and for its effectiveness, even in comparison to more expensive brands.

Pros

  • 👍 Highly effective in eliminating fleas
  • 🐱 Designed specifically for large cats over nine pounds
  • 🏥 No need for a vet's prescription
  • ⏰ Begins working in 12 hours, provides protection for 30 days
  • 💦 Easy to apply and dries quickly

Cons

  • 👃 Has a slightly "chemical" smell, although it dissipates once dried
  • 💲 May seem a bit expensive, but users agree the effectiveness justifies the cost

Should I Buy It?

Based on the overwhelmingly positive reviews and the effectiveness of the product, even in severe infestations, purchasing Advantage II Large Cat flea treatment appears to be a wise decision. The product works fast, keeps working for a month, and requires no prescription. Despite a slightly chemical smell and a higher price range, it is dramatically effective and often outperforms more expensive brands. If flea treatment for large cats is what you need, this product is highly recommended.


  • VERY Effective!
Size: 6-Pack Style: Large Cat only
I recommend to flea-comb your cat at least twice a day for about a week before applying. This reduces the number of living fleas on your cat, so when you apply the product, you don't have 300 fleas "jumping ship" so to speak. I'd gone over my cat so many times with the flea comb, I was coming up with only 1 or 2 fleas per session. Also, use a flea killing spray for areas like under beds, inside sofas, behind furniture, places fleas like to hide. Vacuum everything that you can. Proper application - First make sure your cat is comfortable with the flea comb. Then part a horizontal strip of hair about 1 inch wide at the back of the neck. While holding the part open, apply the product across this strip of exposed skin. Allow to soak for a couple seconds, then gently cover over with surrounding fur, avoiding contact with the liquid. Repeat every month for at least three months in a row to break the life cycle of the fleas, for an indoor-only cat. If your cat goes in and out of he house, it will continuously pick up fleas from outside, and I'd recommend a flea-combing every time they come back inside, and a monthly treatment with Advantage 2 for Cats. For entirely outdoor cats I recommend a flea collar like Seresto, or a monthly treatment with Advantage 2 for Cats. ... show more
Reviewed in the United States on March 17, 2025 by amazoncustomer

  • Good product
Size: 1-Pack Style: Large Cat only
Fleas be gone! Easy to used and not as expensive as other products.
Reviewed in the United States on March 10, 2025 by Mikey M

  • READ THIS
Size: 6-Pack Style: Large Cat only
With my review i am going to address points from reviews posted. This review is only based on my personal experiences. 1. Price. Yes, this product is expensive. However, it's absolutely worth it. It works very well and I've always felt that my cats not suffering is more important than the price tag. Also, here on amazon is significantly cheaper than other places. (Saved $20 buying it here instead of 1800petmeds) 2. Balding. There are a few things that need to be known for this product. Make sure you are using the appropriate dose for your cats. Weigh them. Do not assume their weight. If they are on the borderline, use the smaller dose or dont use all of the larger one. Also dont put it all in one spot. Make a line from the back of their neck to their shoulder blades. 3. "Frontline is cheaper and does the same thing". Incorrect! Frontline is cheaper but in order for frontline to work, the fleas have to bite the animals. This product does not require them to be bitten. 4. "Fleas didnt go away." You cannot expect any flea product to completely rid your home of them. It takes a minimum of 3 months to completely get rid of them if you actively fight against the fleas. You need to vacuum your floors and furniture every day at least for awhile. You also need to keep up with your laundry and wash blankets regularly, including your bedding. And its also very important to be spraying your furniture down with flea spray. RAID or Hotshot work wonders for this! Spray your furniture and bedding down every night. I also spray in the crevices of my apartment because fleas like to hide. 5. "Fleas were going everywhere so i had to give them a flea bath." Do NOT do this. Them jumping off your pets is a GOOD thing! That means the product is working. If you bathe them before the product has time to set it, you just wasted your money. This is why you need to be keeping up with prevention in your home. Theyre jumping off your animal because the product is working. Vacuuming, washing, and spraying is what will combat the infestation. You CANNOT get rid of fleas completely in a short period of time so dont expect a miracle. That's where people get disappointed. Let the product do its job and play catch up for the next few months. And make sure you're keeping up with the doses!! ... show more
Reviewed in the United States on June 20, 2017 by KForbess KForbess

  • Flee fleas
Size: 2-Pack Style: Large Cat only
I’ve been using this flea medicine for over a year. It’s easy to apply. It last about 4 weeks sometimes not. My cat is inside, outside so if I let it go longer I suffer from flea bites also of course Teddy does too.
Reviewed in the United States on April 10, 2025 by 1dennis3

  • Been using Advantage II for years and still happy!
Size: 6-Pack Style: Large Cat only
I've been using Advantage II for our four cats for years. The pricing and convenience of buying on Amazon are perfect for us. I keep this flea medication on our Subscribe and Save all year round. Our cats have never had a bad reaction to this flea medicine, and it's very easy to administer to them. Our cats go outside every day, and we never see fleas. We will definitely continue to use Advantage II through Amazon Subscribe and Save for the foreseeable future! ... show more
Reviewed in the United States on April 2, 2025 by TracieMahan

  • Highly recommended by veterinarians
Size: 6-Pack Style: Large Cat only
I had been buying some of the other high dollar flea and tick medication’s for the cats and dog. It did not take care of the problem. I ended up having to spray my cats with a 50-50 mixture of water and red cider vinegar. I had to Dr my carpets with baking soda Because the fleas had gotten so bad. Not because I hadn’t been trying to do anything about them, but because the other medicines did not work, I was told by the vet that the certain medicines were not working for anybody. He recommended this one. He said it would work and the animals were immune to the others so I’m hopeful. I also spoke to other pet owners and they had the same problems. ... show more
Reviewed in the United States on April 4, 2025 by Storm

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