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Differin

Differin Acne Treatment Gel, 60 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Pack of 2) (Packaging May Vary)

    • Based on 82,368 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon
Arrives Thursday, Jan 30
Order within 20 hours and 43 minutes
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Style: Tube


Size: 30g (60 Day Supply)


Features

  • TARGETS ACNE: Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
  • CLEARS, TREATS & PREVENTS: Differin works differently than other Acne treatments by normalizing skin cell turnover and effectively targets two primary causes of Acne, clogged pores and inflammation
  • RX STRENGTH ACNE RETINOID: Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
  • DERMATOLOGIST RECOMMENDED: Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating Acne
  • REAL RESULTS: In a clinical study, Differin gel provided up to 87 percent reduction in acne breakouts after 12 weeks, which will continue to improve with further use

Description

Differin Gel Acne Treatment contains adapalene, an Rx-strength acne-fighting retinoid that helps clear breakouts where they start (works deep into pores in 5 minutes), helps prevents new acne from forming, and as a result, can restore skin's overall tone and texture. Adapalene is the first over-the-counter active ingredient for acne in more than 30 years. It clears acne with the power of an Rx without the prescription, prevents breakouts, blackheads, whiteheads, blemishes and clogged pores, and can be used to effectively treat acne, or maskne, caused by wearing face masks or facial coverings. When used as directed, you could start to see results in as little as 1 week, and when used every single day, Differin Gel can help reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories).

Item Form: Gel


Scent: Unscented


Brand: Differin


Product Benefits: Anti-Acne


Skin Type: Sensitive


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 4 x 5 x 7 inches; 3.14 ounces


Item model number ‏ : ‎ 0299.024060


Department ‏ : ‎ Beauty & Personal Care


UPC ‏ : ‎


Manufacturer ‏ : ‎ Galderma


Country of Origin ‏ : ‎ Canada


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Thursday, Jan 30

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

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View our full returns policy here.

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Top Amazon Reviews

    • It works if you're patient!
I have been using Differin for over a year now (around 14 months giver or take) and did not publish a review until now. If you want an in-depth review, read on. For the tl;dr version: it works, just stick with it. Btw, I was not paid for this nor was I sent this product (although they should be sending it, given how many tubes I've bought). I had the MOST TERRIBLE acne. No, I'm not talking about a small tiny excuse of a blemish that your friend with great skin complains about when she has her "bad skin" days. My face was RED and PAINFUL. My cheeks were COVERED all the time, and I had no area on my face where acne wouldn't pop up. Nose, brows, chin, jaw, underneath the jaw, you name it. I had tried Curology and while my skin got amazing for the first 6 months, my acne returned with a VENGEANCE. I had tried so many things, clay masks, benzoyl peroxide, salicylic acid, other AHAs and BHAs, sulfur, rosehip oil, and even supplements like zinc and milk thistle, you name it. Nothing worked at all. I was so so embarrassed of my skin, but I couldn't wear makeup either since makeup made my acne SO MUCH worse. I heard about Differin and I figured "well, might as well give this a try cause it can't get any worse". Boy, I was wrong. It did get worse. Much worse. Suddenly I had SO much more acne and I felt like crap. I couldn't believe my skin could get worse, but it did. Differin was the only thing I was using so I knew this was it. I was depressed but I stuck with it, cause I wanted to test it for at least 4 months. I thought I might as well test the claim, since my skin is so bad already. The first month was really really bad. It brought all underlying acne to the surface i.e. the purge phase. It did the purging for 3-4 months, but the first month was THE WORST. Not gonna lie to you, that first month will probably be the worst skin you've had in your life. Your skin will become SO SENSITIVE! Anticipate that! My skin has never been sensitive to products but while using this, my regular moisturizers and masks would sting like crazy (get stuff with no fragrance/alcohol or acids!). It didn't affect my skin in any other way, it just stung a lot. Oh, and I used to get my upper lip and brows waxed. Not with this you can't, the wax will tear off your skin since it gets much more sensitive. I learned the hard way. ONLY do threading! However, after I waited out the terrible, terrible first month, I slowly began to see improvements. Marginal, though. I had acne, but I probably had just a tad less. And it continued that way, it kept improving. Eventually, my skin was so much clearer than before! I still had acne, mind you, it's not a miracle drug, but it was few and far in between. There would be times when I had no active acne, which was HUGE for me!! My face usually looked like a connect the dots game. However, I did hit a plateau. This worked phenomenally at reducing my ugly acne all over my face to a few zits here and there, however, my issue was deeper than that. Eventually, I went to a doctor and got on spironolactone. Now, I am both on my Spiro and this. The combo of these two have made my skin so clear! I could have never imagined this day! I still need to use this, I have noticed my Spiro is not enough to keep zits at bay and if I skip a couple of nights putting on differin, new zits come up. I am so much happier now that I don't have zillions of gross zits on my face. I still get zits if I eat sugar or near my period but man, I am a long way from before! I have a few blemishes left over from before but I honestly don't care, my skin looks wayyy better. I can hide my blemishes with a sheer foundation of spot concealing if I want. So if you've read till the end, the lesson is: be PATIENT and be realistic! Your acne did not appear overnight and will not disappear overnight. If you stick with this, it WILL work. However, your mileage may vary. My acne was extremely bad, so after I hit my "acne plateau" I went to the doctor. If your acne is not as bad, it's likely differin is all you need for clear skin! If you're on the fence, confused, depressed, frustrated and/or can't afford a doctor, it's worth a shot! Just be patient and gentle with your skin! ... show more
Reviewed in the United States on June 9, 2018 by Biryani
    • Differin compared to generic Taro Adapalene
Style: Tube Size: 30 Day Supply
So I'm sure a lot of people, like me, are wondering how this compares to the generics, like Taro adapalene. (I noticed there was another generic too, but because it was more expensive than the Taro, and also made in India, I decided to pass on it) So I will say both products seem to be just as effective. Both are made in Canada and contain nearly identical inactive ingredients. If I was doing a blind test, I'd definitely give this Differin the edge however. The Differin has the edge for two main reasons. First, I noticed immediately when applying the Taro that it burned more on my skin. While this wouldn't happen on day 1, your skin will likely be dry and irritated while the product does it's thing. So any extra irritation is more pronounced. Second, I also noticed the Differin absorbs/dries much faster than the Taro. While this may not be a big deal, it is nice if you want to put it on right before bed. I also noticed the Differin tube has a smaller opening, so it's less likely you'll over apply. All that being said, it currently costs around twice as much. And because I'm doing my entire face, when I reorder I'll likely go with the Taro. But, if you're just doing a small area and aren't going though a lot, it might be worth the extra to go with the Differin, especially if you have very sensitive skin or need something that's fast drying. ... show more
Reviewed in the United States on December 11, 2024 by Octavius
    • Waiting for the results
Style: Tube Size: 30 Day Supply
Review Image by Dr Jisu Kim Dr Jisu Kim
I saw many reviews mentioning a purging period, which made me nervous, but there were even more reviews saying it gets better if you endure it, so I decided to give it a try. It’s only been a few days since I started using it, and sure enough, I’m also experiencing purging. Once this period of patience is over and my skin improves, I’ll post an additional review. ... show more
Reviewed in the United States on January 20, 2025 by Dr Jisu Kim Dr Jisu Kim
    • Some important things to know before starting....
Review Image by Private Profile Private Profile
Review Image by Private Profile Private Profile
Review Image by Private Profile Private Profile
Here is what I did to avoid the fate of purging and negative skin rashes..... Don't: 1) Don't use on raw EXFOLIATED skin. Wait a couple days after exfoliating. 2) Don't use a SUDSING cleansing soap prior. Use a mild hydrating Cleanser. 3) Don't use after getting your skin waxed or shaved. 4) Avoid hot water and steam before use. 5) Do NOT go stand in the sun after applying (retin works by thinning the top layer of your skin which is usually used for protection against the sun). Don't take your chances! 6) do not apply to eyelids or neck or other thin skin areas including the inside of your wrists. You can apply Vaseline to these areas if needed to protect them. 7) don't freak out if your face flakes and don't scrub the flakes off. Moisturizer is your friend. 8) don't scratch at your skin if itches or burns, stay calm, rinse it off with cool water. Apply a gentle cream and then apply a cool wash cloth. Consider diluting before using again. 9) don't assume because your neighbor next door can use twice a day on fresh scrubbed skin with no adverse effects, that the same will be true for you. Adverse skin reactions can take weeks or months to heal from. 10) do NOT apply generously all over your skin. Pea size only on face. Do: 1) plan on using once or twice a week at first for the first month. Remember "sparingly" is your motto. 2) Have a natural moisture barrier on your face first. Be sure you have not scrubbed your skin raw or clean prior and make sure face is danp prior to applying. 3) if you have ultra sensitive skin, apply a gentle moisturizer FIRST before applying differin. Allow to dry before applying differin. 4) do apply a creamy moisturizer after if needed. Wait five minutes before you do. 5) do also apply sunscreen RELIGIOUSLY if you will be outdoors. So important!!!! 6) do research "purging" and what you can do to minimize or avoid it. 7) do remember that this product is a MEDICATION and not your typical OTC cream. Use sparingly and with caution. 8) do remember that moisture is your friend. After cleansing, avoid drying your skin with towels. Avoid air drying as well. 9) do remember that with this product "less is more". It is potent stuff! Once or twice a week treatments alone will make a difference. 10) keep a good repair Cream on hand in possible event of harsh reaction or irritated skin. I recommend "first aid beauty ultra repair cream". This stuff is amazing. Hydrocortisone cream can also be used. MOST IMPORTANTLY: it takes 6-12 weeks of patient and measured use before seeing positive long term results for acne. It can take up to a year before seeing positive results for aged and wrinkled skin. MY RESULTS: I started out at a twice a week and had no reaction except for mild redness, itching and tingling the following two days afterwards. When I tried to increase to three days a week, I started having issues. The solution to this was to revamp my skin care routine (listed below). After that, I was able to switch pretty rapidly to nightly use. The GAME CHANGER was adding First Aid Ultra Hydrating Cream. I've included my before and six week after photos. My acne is gone and my pores most definitely shrunk. I used the same room and lighting and I notice that my skin has become much brighter and lighter. My guess is in removing the thing top layer of skin, we no longer see the old tanned skin I had. So far, I am happy with the results. I am 38 years old. My long term goal is to prevent deep wrinkles and shrink my pores and hopefully reduce white Milia bumps under my eyes as well as all random acne and age spots. I know from researching this can take months and years so I'm feeling patient. MY CURRENT DIFFERIN APPLICATION: My morning routine: - CereVe Hydrating Cleanser - After rinsing, I apply Timewise Vitamin C Serum with the added F acid. - Then, I apply a thin layer of Sunscreen: La Roche-Posay Anthelios with Mexoryl SX OR CeraVe SPF 30. *note: I believe the Vitamin C Serum helped with quicker skin cell turnover rate to prevent purging. In the evenings: - I double cleanse: first I use Yes To Coconuts Uktra Hydrating Creme Cleanser. After I rinse that off, I cleanse with CeraVe Hydrating Facial Cleanser. - I allow skin to stay damp. - I then apply a pea size amount of differin to my face (never on neck or eyelids). - after about minutes, I follow that with First Aid Beauty Ultra Repair Cream. - I apply CeraVe Skin renewing Serum to my eyes and neck and chest. - note: I only use retin A products at night to decrease sun sensitivity. In the mornings, I use all my other acids and Vitamin C. Be aware that most of the negative reviews on here are mostly due to user error and lack of knowledge in the product. There is no reason to have terrible breakouts or harm your skin. I'm horrified people are using this on their NECK right away. Poor skin! This is a potent product. Good luck! ... show more
Reviewed in the United States on January 1, 2018 by Private Profile Private Profile

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