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Frontline

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs., 3 Treatments

    • Based on 82,041 reviews
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Availability: In Stock.
Fulfilled by Amazon
Arrives Sunday, Dec 1
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Size: 3 Count


Color: Purple Box


Features

  • Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
  • Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
  • Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
  • FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
  • Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
  • Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
  • Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

Description

Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.

Brand: Frontline


Item Form: Stick


Scent: Unscented


Age Range (Description): All Life Stages


Item Weight: 1.6 Ounces


Active Ingredients: fipronil and (S)-methoprene


Item Volume: 339 Milliliters


Target Species: Dog


Allergen Information: Abalone Free


Dog Breed Size: Large


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 5.75 x 0.75 x 4.5 inches; 1.6 ounces


Manufacturer recommended age ‏ : ‎ 1 month and up


Item model number ‏ : ‎ 72219


Department ‏ : ‎ Insect Control


Date First Available ‏ : ‎ September 2, 2004


Manufacturer ‏ : ‎ Boehringer Ingelheim Animal Health


Country of Origin ‏ : ‎ Germany


Best Sellers Rank: #19 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Dog Flea Drops


Item Weight: 1.6 ounces


Department: Insect Control


Manufacturer: Boehringer Ingelheim Animal Health


Country of Origin: Germany


Item model number: 72219


Date First Available: September 2, 2004


Item Package Dimensions L x W x H: 5.83 x 4.38 x 0.75 inches


Item Dimensions LxWxH: 5.75 x 0.75 x 4.5 inches


Item Weight: 1.6 Ounces


Brand Name: Frontline


Target Audience Keyword: dogs, ( reptiles | amphibians ), dogs|( reptiles | amphibians )


Directions: Directions for Use Step 1. To REMOVE Applicator 1. Use scissors to separate one blister; 2. Use scissors to cut along dotted line; 3. Peel down foil to remove the applicator. Step 2. OPEN Applicator. Hold upright with foil side toward you and snap applicator tip. Step 3. APPLY FRONTLINE Plus. Part the dog’s hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the dog’s skin. Do not apply on top of the hair coat. Avoid contact with treated area until dry. Do not allow your dog to ingest the product. Do not apply to dogs weighing less than 45 lbs. or younger than 8 weeks of age. Do not use more than one application per dog per month. Frequency Use monthly to control fleas and ticks. Do not reapply FRONTLINE Plus for 30 days.


Country of Origin: France


Warranty Description: only for dog


Model Name: FRONTLINE Plus for Dogs Medium Dog (23-44 pounds) Flea and Tick Treatment, 3 Doses


Color: Purple Box


Size: 3 Count


Material: S-Methoprene, Fipronil


Age Range Description: All Life Stages


Care Instructions: Do not use on kittens under 8 weeks of age or 1.5 lbs


Number of Items: 1


Style: Large Dog (45-88 lbs.)


Breed Recommendation: Large Dog, 45 to 88 pounds


Included Components: Package includes 3 applicators


Specific Uses for Product: Parasites


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Sunday, Dec 1

This item is non-returnable:

Non-returnable due to Hazmat safety reasons

View our full returns policy here.

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Top Amazon Reviews

    • Works, safe, but not instant results
Size: 3 count Color: Orange Box
Super easy to use and apply. No smell, no unusual behavior from our dog afterwards. Keep in mind, this does not work immediately, and the instructions even state this fact. It takes time to work. By month three, after the third application our flea problem was completely gone. Before we started using this product the fleas has gotten so bad that they were in multiple areas of the house the dog had been. Using only this product and vacuuming and cleaning regularly completely eradicated the nuisance. Most importantly, our manchester terrier is completely healthy and fine after usage, and pest free. ... show more
Reviewed in the United States on April 12, 2024 by JM
    • Kills fleas
Size: 3 Count Color: Purple Box
If you've had a pet with fleas you know it quickly becomes a nightmare. After finding your socks and ankles have fleas and bites you snap. You take matters in your own hands. But they somehow dont die. No. Tiger pits, dropping anvils, 12 gauge....they always survive, like they're thumbing their nose at you. My neighbor came by after hearing a couple of frags going off in my home. The little zombies still hadn't died and I was filled with rage, frustration, and flea bites. He recommended Frontline. This stuff works. It makes the little vampires sterile. At first there's no break. But after 3 days I did notice a small difference. 10 days in I barely saw a flea. 14 days until several years later (now) fleas have been non existent. It does kill ticks, and it kills fleas eggs, or maybe flea hatchlings. Don't remember. What I do remember is this stuff works great. And my dog is happier ... show more
Reviewed in the United States on May 9, 2024 by D
    • Works great!
Size: 8 Count Color: Purple Box
This is a great product for keeping ticks off my dog! There is no odor and it is easy to apply topically. Will continue to purchase.
Reviewed in the United States on June 25, 2024 by Terry Tamraz
    • Your Safest Bet For A Product You Wish You Didn't Need.
Size: 6 Count Color: Purple Box
Allow me to caveat this review by saying out of 700 plus reviews this is the most difficult to write as I despise having to use pesticides on our dogs. That said, we live in Tick and Flea central, surrounded by deep woods and our bulldogs are in every sense of the word family and we do whatever we must to protect them. That said if you're reading these reviews your dog or dogs are your heart too and using these products is a difficult choice to make, but it's one we have to make. On that note, it's my hope the following information has some value for you. Frontline was first put into clinical trials in 1985 shortly after the discovery of it's active ingredient Fipronil. To it's credit Frontline has maintained the safest albeit not the most effective treatment for fleas and ticks. However, the more effective products pose a significantly greater risk to your dog. It's a slippery slope, but in evaluating what's best for your dog by providing the highest level protection with the lowest risk Frontline and FrontLine Plus are in my opinion your best bet. Most tick and flea products contain Permethrin which may also be listed as Lyclear or Nix as the active ingredient. Permethrin is a lethal neurotoxin that flows through the dogs circulatory system and flushes into every major organ - including the brain where it can do dire damage. Thousands of dogs die every year from Permethrin. Although the FDA has mandated a minimal use not to exceed 750PPM companies continue to ignore the guidline because it's cheap and effective, and sadly it's our dogs that pay the price. What makes Permethrin so dangerous is that it can't distinguish between insects and mammals which of course includes human beings. It's been known to be lethal to cats since the 1970's. In fact it's so deadly to cats that even a slight transfer from dog to cat can result in seizures, brain damage and death. Permethrin is volatile as well - meaning it's airborne properties pose a threat to all who breath it in - humans included. Frontline on the other hand uses Fipronil. Fipronil is an insecticide. Like any chemical of this nature it can be lethal at too high of a dose. However studies including those from the Department of Environmental Conservation have determined time and time again that as long as the amount of Fipronil is at the correct dose for the weight and size of your dog toxicity is far easier to avoid and the product much safer for your dog. Unlike Premethrin, Fipronil is absorbed into the hair follicles and oil glands only. It is not absorbed into the dogs system nor is it volatile so you and your beloved pets and children can breath easy. The second active ingredient in FrontLine Plus is Methoprene which is a long existing and time proven IGR (insect growth regulator) it's distributed exactly like Fipronil but only acts on flea and tick eggs and Larvae - this is important because it kills these vermin at the start of a new life cycle. What is more, the diseases that ticks carry now are infinitely more serious than the dreaded Lime disease - which for decades was the only concern. Competitors to Frontline (and some Vets selling other products) claim that fleas and ticks have become resistant to Frontline - However these pests have become resistant to some degree to all pesticides and no independent research exists to confirm this claim. I can assure you I've researched this in the greatest depth. The bottom line is this - all of these products pose a risk. The wise choice is to minimize that risk in your effort to protect your best friend from the diseases these vermin carry. Again, these diseases can be infinitely more lethal than the ingredients of the protection. To that end your safest and most effective choice is Frontline or Frontline Plus. In the event your pet has a bad reaction to Frontline products these are the symptoms you would see: * Restlessness * Itching * Vomiting * Difficulty Breathing * Lethargy Should these symptoms occur, of course take your pet to your Veterinarian or emergency clinic immediately. It should be a comfort to know that unlike the toxic ingredients in most other flea and tick control products severe reactions to both Fipronil and Methoprene are rare. ... show more
Reviewed in the United States on August 18, 2012 by Peter Suslock
    • Great product
Size: 3 count Color: Orange Box
No smell, easy to open and use. Effective treatment for pests on pets
Reviewed in the United States on June 29, 2024 by Leah penn
    • Always works!
Size: 3 Count Color: Purple Box
As I had our dog on “all natural” flea & tic preventative, our big boy had tics. Not happy! I tried to stay away from pesticides. Well it didn’t work out so good. Lime disease can be fatal, so I’m back to frontline plus & very happy. Sorry I ever switched products, but lesson learned! Thankfully no fleas! This product always works & tics & fleas are bad in Missouri. ... show more
Reviewed in the United States on June 24, 2024 by Linda
    • It works
Size: 3 Count Color: Purple Box
It worth the money? Our dog was full of fleas, after a shower and applying this they are all gone and so far not a single one is back 👌
Reviewed in the United States on June 27, 2024 by Nikoletta Lopez
    • Need more often
Size: 3 Count Color: Purple Box
I've been putting this on my boys for a few years now but it seems like I need to apply it more often - like once a month. When it is fresh - they still get ticks on them but if they bite they die instantly and I still have to pick the ticks off. It works, but if you're in a heavily tick'd area, then be prepared to apply regularly. It does create their hair along their back kind of greasy for a few days and I have to keep my kids from petting them, and try to not let the dogs roll around outside with a fresh batch. All in all - it works just fine for the price. Not insanely expensive and not the super highest quality. ... show more
Reviewed in the United States on June 17, 2024 by Sierra

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